منابع مشابه
Proteomics strategies for target identification and biomarker discovery in cancer.
The revolution in genomics and proteomics has produced complex technologies enabling an insight into the functional effectors of cellular processes. In oncology these technologies lead to the identification of biological markers which may provide the starting point for the development and identification of diagnostic tests and therapeutic targets. To identify and validate reliable tumor markers...
متن کاملChemical proteomics applied to target identification and drug discovery.
Introduction In the past decade, DNA sequencing of multiple organisms has provided us with our first look at complete lists of protein products expressed from a whole genome. The field of proteomics is now challenged with the task of elucidating the cellular functions of these proteins in both normal and pathological processes (1–3). Several proteomic techniques, such as 2-dimensional gel-elect...
متن کاملTarget Identification based on DSmT
An approach providing fast reduction of the full ignorance in the target identification process is proposed. It uses the new Dezert-Smarandache theory (DSmT) for plausible and paradoxical reasoning, combined with fuzzy set theory. The approach utilizes the information from the adjoint sensor and the additional information obtained from a priori defined objective and subjective considerations. A...
متن کاملgel-based proteomics
proteomics has emerged since 1995 for studying the total proteome of cells, tissues, or organisms at any condition. the study of proteins has a fundamental importance because they are the functional and final molecules of the gene expression process and proteomics could be a valuable technique for achieving this purpose. mass spectrometry is a complementary technique for proteomics that allows ...
متن کاملParameters Identification of an Experimental Vision-based Target Tracker Robot Using Genetic Algorithm
In this paper, the uncertain dynamic parameters of an experimental target tracker robot are identified through the application of genetic algorithm. The considered serial robot is a two-degree-of-freedom dynamic system with two revolute joints in which damping coefficients and inertia terms are uncertain. First, dynamic equations governing the robot system are extracted and then, simulated nume...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m309039200